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Our VISION is to bring ACCURACY, EFFICIENCY, and SIMPLICITY to the glycoanalytic process.
Publications
  1. Lapadula, A.J., Hatcher, P.J., Hanneman, A.J., Ashline, D.J., Zhang, H., Reinhold, V.N. Congruent Strategies for Carbohydrate Sequencing. 3. OSCAR: An Algorithm for Assigning Oligosaccharide Topology from MSn Data. Analytical Chemistry, 2005, 77(19), 6271-9.
  2. Ashline, D., Singh, S., Hanneman, A., Reinhold, V. Congruent Strategies for Carbohydrate Sequencing. 1. Mining Structural Details by MSn. Analytical Chemistry, 2005, 77(19), 6250-62.
  3. Hanneman, A.J., Rosa, J.C., Ashline, D., Reinhold V.N. Isomer and Glycomer Complexities of Core GlcNAcs in Caenorhabditis elegans. Glycobiology, 2006, 16, 874.
  4. Ashline, David J.; Lapadula, Anthony J.; Liu, Yan-Hui; Lin, Mei; Grace, Mike; Pramanik, Birendra; and Reinhold, Vernon N. Carbohydrate Structural Isomers Analyzed by Sequential Mass Spectrometry. Analytical Chemistry, 2007, 79, 3830.
  5. Prien JM, Huysentruyt LC, Ashline DJ, Lapadula AJ, Seyfried TN, Reinhold VN. Differentiating N-linked Glycan Structural Isomers in Metastatic and Non- Metastatic Tumor Cells using Sequential Mass Spectrometry. Glycobiology, 2008, 18(5), 353-366.
  6. Anthony, R.M., Nimmerjahn, F., Ashline, D.J., Reinhold, V.N., Paulson, J.C., Ravetch, J.V. Recapitulation of Intravenous Ig Anti-Inflammatory Activity with a Recombinant IgG Fc. Science, 2008, 320, 373-376.
  7. Zavareh, R.B., Lau, K.S., Hurren, R., Datti, A., Ashline, D.J., Gronda, M., Cheung, P., Simpson, C.D., Liu, W., Wasylishen, A.R., Boutros, P.C., Shi, H., Vengopal, A., Jurisica, I., Penn, L.Z., Reinhold, V.N., Ezzat, S., Wrana, J., Rose, D.R., Schachter, H., Dennis, J.D., Schimmer, A.D. Inhibition of the sodium/ potassium ATPase impairs N-glycan expression and function. Cancer Research, 2008, 68(16), 6688-6697. Erratum in: Cancer Research, 2008, 68(18), 7692.
  8. Prien, J.M., Ashline, D.J., Lapadula, A.J., Zhang, H., Reinhold, V.N. The High Mannose Glycans from Bovine Ribonuclease B Isomer Characterization by Ion Trap MS. J. Am. Soc. Mass Spectrom., 2009, 20, 539-556.
  9. Berenson, C.S., Nawar, H.F., Yohe, H.C., Castle, S.A., Ashline, D.J., Reinhold, V.N., Hajishengallis, G., Connell, T.D. Mammalian cell ganglioside-binding specificities of E. coli enterotoxins LT-IIb and variant LT-IIb(T13I). Glycobiology, 2010, 20(1), 41-54.
  10. Prien, J. M.; Huysentruyt, L. C.; Ashline, D. J.; Lapadula, A. J.; Seyfried, T. N.; Reinhold, V. N. "Differentiating N-linked Glycan Structural Isomers in Metastatic and Non-Metastatic Tumor Cells using Sequential Mass Spectrometry", Glycobiology, 2008, 18, (5), 353-66.
  11. Prien, J.M.; Ashline, D.J.; Lapadula, A.J.; Zhang, H.; Reinhold V.N. “The High Mannose Glycans from Bovine Ribonuclease B: Isomer Characterization by Ion Trap MS”, JASMS, 2009, 20(4), 539-56.
  12. Prien, J.M.; Prater, B.D.; Cockrill, S.L. “A multi-method approach toward de novo glycan characterization: A Man-5 case-study”, Glycobiology, 2010, 20(5), 629-47.
  13. Prien, J.M; Prater, B.D.; Qiang Qin; Cockrill, S.L. “Mass spectrometric-based stable isotopic 2-aminobenzoic acid glycan mapping for rapid glycan screening of biotherapeutics”, Analytical Chemistry, 2010, 82(4), 1498-508.
  14. Prien, J.M; Prater, B.D.; Qiang Qin; Cockrill, S.L. “Automated glycan permethylation preparation facilitated by liquid handling systems”, Analytical Biochemistry, 2010, (submitted)

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